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Let's get to know grape seed extract.

grape seed extract (Vitisvinifera Linn.) is a substance consisting of Proanthocyanidins which has high antioxidant activity Can help increase blood circulation It inhibits the destruction of collagen, which is an important part of cell membranes. In addition, grape seed extract is beneficial to the heart and nervous system. and other systems throughout the body. The important substances found in grape seed extract are classified as bioflavonoids, namely Oligomeric Proanthocyanidin (OPCs), which is one of the flavonoid families found in abundance in seeds and flowers. and the peel of hard-shelled fruits

 

What is special about OPC ?

OPC is a water-soluble antioxidant. Its antioxidant power is 20 times higher than vitamin C and 50 times higher than vitamin E, so it has been dubbed a highly effective antioxidant. (Super-antioxidant) In addition, when eating OPC together with Vitamin C, it will help enhance the effect of the vitamin C that has been used to restore it to use again. Therefore, some people call OPC a Vitamin C cofactor.

OPC can penetrate every part of the body's cells well. Even brain cells because they can pass through the blood-brain barrier (Blood Brain Barrier) are therefore a dietary supplement that takes good care of holistic health.

Grape seed extract can extract OPC at a concentration of 80-95%.

 


Benefits of OPC substances to the body

     Helps brighten the skin. Restore youthfulness to the skin. There is research that shows that test subjects who ate OPC substances from grape seed extract (Grapeseed extract) will have blemishes and dark spots from the sun. significantly decreased The brightness of the skin in areas of dark spots increases. It also helps protect the skin from UV light damage and significantly moisturizes the skin. In addition, eating OPC from grape seed extract together with Vitamin C can help reduce facial wrinkles more than eating Vitamin C alone.

In addition to taking care of your skin to make it bright and youthful. The antioxidant power of OPC also has a positive effect on many other systems of the body, such as

Cardiovascular system 

     Helps increase Nitric oxide (NO), causing blood vessels to expand well, helping to reduce blood pressure. Reduce antioxidants Helps reduce the formation of (LDL), reducing the risk of coronary heart disease. Increases the strength of blood vessel walls, reducing the chance of and reduce pain from varicose veins

Reducing cause of diabetes

     Inhibits enzymes Alpha-glucosidase sugar digester Reducing sugar being absorbed into the bloodstream Helps stimulate the secretion of GLP-1 and DPP-4, binding to starchy foods, causing starch to be digested more slowly, helping to reduce blood sugar levels.

Nervous system

     OPC and resveratrol in grape seeds can cross the blood-brain barrier. Therefore, it can reduce free radicals in the nervous system, reducing the degeneration of nerve cells. Promotes the functioning of the nervous system By stimulating CREB (cAMP response element binding), which is important for converting short-term memory into long-term memory.

Immune system

      Reduce the production of inflammatory substances IL-1β, IL-6, and TNF-α. Reduce the amount of pathogenic bacteria in the intestines and Reduce intestinal inflammation, increase Lactobacillus and Bifidobacteria. increase secretion immunoglobulin Build immunity for the intestines

Anti-cancer

     Inhibits abnormal changes in cells in the body by many mechanisms that are factors in cancer. Reduce damage to normal cells from free radicals that occur from cancer treatments such as chemotherapy or radiation.

Precautions for taking Grape seed extract

      Grape seed extract has the effect of breaking up blood clots. Therefore, taking it together with drugs that have an effect on blocking the function of blood platelets. Anticoagulants or anticoagulants may increase the risk of bleeding and bruising. Examples include Warfarin, Aspirin, Clopidogrel.

      In addition, Grape seed extract also has the effect of inhibiting the liver enzyme that is responsible for changing the condition of many medicines (potent inhibitor of CYP3A4), causing the drug levels in the blood of some medicines to increase to the point that they may act too much and cause side effects. You should consult your doctor or pharmacist. Every time before taking Grape seed extract with other medicines Examples of drugs that are changed through CYP3A4 include Diazepam, Loratadine, Cimetidine.